γ h2ax (Cell Signaling Technology Inc)
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γ H2ax, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/h2ax/pmc13050126-128-5-9
Average 86 stars, based on 1 article reviews
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1) Product Images from "Gynostemma pentaphyllum -derived extracellular vesicles alleviate skin aging by destabilizing STING"
Article Title: Gynostemma pentaphyllum -derived extracellular vesicles alleviate skin aging by destabilizing STING
Journal: Bioactive Materials
doi: 10.1016/j.bioactmat.2026.03.010
Figure Legend Snippet: The application of GPEVs alleviate d histopathological injury in UVB- irradiated Balb/C mice. Mice were randomly divided into five groups and subjected to a graded escalation of UVB irradiation doses in the presence or absence of GPEVs (n = 6 for each group). (A) The flow chart represents the establishment of UVB irradiation-induced skin aging model and GPEVs treatment design. (B) The skin moisture levels of mice from each group were recorded throughout the duration of the experiment. (C) Representative images of the mouse dorsal skin from each group. (D) The semi-quantitative macroscopic scoring of skin aging was assessed in each group. (E) The representative H&E images of mice skin from each group. Scale bar: 200 μm. (F) The quantification of the epidermis thickness in all five groups. (G and H) Representative immunofluorescence images and quantification of γ-H2AX in skin tissue sections. The analysis of γ-H2AX fluorescence was conducted utilizing Image J software. Data are represented as means ± SEM. Statistical analysis was performed using one-way ANOVA followed by Bonferroni post hoc test. Not significant (ns), ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.
Techniques Used: Irradiation, Immunofluorescence, Fluorescence, Software
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